Pediatric Schwartz Equation:
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The Pediatric Schwartz Equation estimates creatinine clearance for children and adolescents aged 1-18 years. It provides a reliable assessment of kidney function in pediatric patients using height and serum creatinine measurements.
The calculator uses the modified Schwartz equation:
Where:
Explanation: The equation estimates glomerular filtration rate in children based on the relationship between height, serum creatinine, and kidney function.
Details: Accurate creatinine clearance estimation is essential for diagnosing kidney dysfunction in children, monitoring kidney development, and adjusting medication dosages for pediatric patients.
Tips: Enter height in centimeters, serum creatinine in mg/dL, and age between 1-18 years. All values must be valid (height > 0, creatinine > 0, age 1-18).
Q1: Why is height used in pediatric CrCl calculation?
A: Height correlates well with muscle mass and kidney size in children, making it a reliable parameter for estimating kidney function in pediatric populations.
Q2: What are normal CrCl values for children?
A: Normal values vary by age but generally range from 70-140 mL/min/1.73m², with higher values in younger children and gradual decline toward adult norms.
Q3: When should this equation not be used?
A: Not suitable for infants under 1 year, patients with rapidly changing kidney function, or those with extreme body compositions.
Q4: How does pediatric CrCl differ from adult calculations?
A: Pediatric equations account for growth and development, using height as a key variable rather than adult-specific factors like gender and race.
Q5: Can this be used for medication dosing in children?
A: Yes, this calculation helps guide appropriate drug dosing for medications cleared by the kidneys in pediatric patients.