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Cornell/Schwartz Formula:
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The Cornell/Schwartz formula is a pediatric-specific equation used to estimate creatinine clearance (CrCl) in children. It provides a simple and reliable method for assessing kidney function in pediatric populations using height and serum creatinine measurements.
The calculator uses the Cornell/Schwartz formula:
Where:
Explanation: This formula is specifically designed for pediatric patients and accounts for the relationship between height, muscle mass, and creatinine production in children.
Details: Accurate creatinine clearance estimation in children is essential for detecting renal impairment, monitoring kidney function in chronic conditions, and adjusting medication dosages for renally excreted drugs.
Tips: Enter height in centimeters and serum creatinine in mg/dL. Ensure both values are positive numbers. This calculator is specifically validated for pediatric use.
Q1: What age range is this formula appropriate for?
A: The Cornell/Schwartz formula is validated for use in children and adolescents, typically from 1-18 years of age.
Q2: How does this differ from adult creatinine clearance formulas?
A: Pediatric formulas account for the changing relationship between height, muscle mass, and creatinine production as children grow, unlike adult formulas that use fixed coefficients.
Q3: What are normal CrCl values in children?
A: Normal creatinine clearance in children varies by age and body size, but generally ranges from 70-140 mL/min/1.73m², with higher values in younger children.
Q4: When should this formula not be used?
A: Avoid using in infants under 1 year, patients with rapidly changing renal function, severe malnutrition, or amputees. Consider 24-hour urine collection for precise measurement in complex cases.
Q5: How often should CrCl be monitored in pediatric patients?
A: Frequency depends on clinical context - more frequent monitoring for patients with known renal disease, those receiving nephrotoxic medications, or during acute illness.